化合物简介
Vinyl ether, also known as divinyl ether, divinyl oxide, Vinethene (pharmaceutical trade name) and ethenoxyethene (IUPAC), is a clear, nearly colorless, volatile liquid which was briefly used as an inhalation anesthetic. It can be cyclopolymerized by itself and serves as a cross-linker in copolymerizations.
Much to the dismay of some pharmacologists, the synthesis and isolation of pure vinyl ether proved to be a difficult challenge for chemists; vinyl ether was suspected to be a nearly ideal anesthetic as its structure was the combination of an alkene and an ether. In practice, vinyl ether proved to have favorable properties that allowed its brief usage as an anesthetic; on the other hand, it left many unimpressed. Aggravated by the issue of potentially toxic degradation over long-term storage and possible hepatic toxicity, vinyl ether began to leave the operating theater. Today, vinyl ether is a relic in the field of anesthesiology; however, the analytical techniques used to study its pharmacology laid the groundwork for the testing of new anesthetic agents.
Much to the dismay of some pharmacologists, the synthesis and isolation of pure vinyl ether proved to be a difficult challenge for chemists; vinyl ether was suspected to be a nearly ideal anesthetic as its structure was the combination of an alkene and an ether. In practice, vinyl ether proved to have favorable properties that allowed its brief usage as an anesthetic; on the other hand, it left many unimpressed. Aggravated by the issue of potentially toxic degradation over long-term storage and possible hepatic toxicity, vinyl ether began to leave the operating theater. Today, vinyl ether is a relic in the field of anesthesiology; however, the analytical techniques used to study its pharmacology laid the groundwork for the testing of new anesthetic agents.
基本信息
- 中文名称:
- 二乙烯基醚
- 中文别名:
- 乙烯氧乙烯
- 英文名称:
- Vinyl ether
- 英文别名:
- divinyl oxide;
vinyloxyethylene;
divinyl ether;
1,1′-oxybisethene;
Vinydan;
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- CAS号:
- 109-93-3
- 分子式:
- C4H6O
- 分子量:
- 70.08980
- 精确质量:
- 70.04190
- PSA:
- 9.23000
- LogP:
- 1.29000
分析方法
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共找到 1 个分析方法
柱型 | 活性相 | 温度 (°C) | 保留指数 (I) | 参考文献 |
---|---|---|---|---|
毛细管柱 | Methyl Silicone | 480. | Zenkevich, 1996 |
物化性质
- 密度:
- 0.769g/cm3
- 熔点:
- 133-136 °C(lit.)
- 沸点:
- 28.3ºC at 760mmHg
- 闪点:
- >110°C
- 折射率:
- 1.393
- 储存条件:
- 库房通风低温干燥,与氧化剂、酸类分开存放
- 蒸汽压:
- 676mmHg at 25°C
安全信息
- 危险类别:3.1
- 海关编码:2909199090
- 危险品运输编码:1167
- WGK Germany:3
- 危险类别码:R36/37/38
- 安全说明:S26; S36/37/39
生产方法及用途
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用途
用作麻醉剂,用于生产乙烯-氯乙烯共聚物。