核磁无明显杂峰
CAS NO. | 480998-12-7 | |
英文品名 | INNO-206 monohydrochloride | |
中文品名 | INNO-206 monohydrochloride | |
分子式 | C37H42N4O13.HCl | |
分子量 | 787.21 | |
规格/纯度 | 98% | |
供应能力 | can supply g scale | |
别名 | INNO-206 HCl salt; INNO206 HCl salt; Aldoxorubicin | |
产品简述 | Aldoxorubicin, also known as INNO-206, is the 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin (DOXO-EMCH) with antineoplastic activity. | |
详细说明 | Aldoxorubicin, also known as INNO-206, is the 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin (DOXO-EMCH) with antineoplastic activity. Following intravenous administration, doxorubicin prodrug INNO-206 binds selectively to the cysteine-34 position of albumin via its maleimide moiety. Doxorubicin is released from the albumin carrier after cleavage of the acid-sensitive hydrazone linker within the acidic environment of tumors and, once located intracel |