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Aldoxorubicin Hydrochloride_CAS:480998-12-72017-07-17
产品属性

CAS号:480998-12-7

重量(克):500g

价格(元):询价

时间:2017-07-17 09:15:23

交易状态:等待报价

产品信息

核磁无明显杂峰

 

 

CAS NO. 480998-12-7 structure
英文品名 INNO-206 monohydrochloride
中文品名 INNO-206 monohydrochloride
分子式 C37H42N4O13.HCl
分子量 787.21
规格/纯度 98%
供应能力 can supply g scale
别名 INNO-206 HCl salt; INNO206 HCl salt; Aldoxorubicin
产品简述 Aldoxorubicin, also known as INNO-206, is the 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin (DOXO-EMCH) with antineoplastic activity.
详细说明 Aldoxorubicin, also known as INNO-206, is the 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin (DOXO-EMCH) with antineoplastic activity. Following intravenous administration, doxorubicin prodrug INNO-206 binds selectively to the cysteine-34 position of albumin via its maleimide moiety. Doxorubicin is released from the albumin carrier after cleavage of the acid-sensitive hydrazone linker within the acidic environment of tumors and, once located intracel
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