化合物简介
Piracetam (sold under many brand names) is a nootropic drug in the racetams group, with chemical name 2-oxo-1-pyrrolidine acetamide. It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid. Piracetam is a cyclic derivative of GABA. Presently piracetam is used in many European countries, Asia and South America. In the United States, it is not approved by the US Food and Drug Administration for any medical use and it is not permitted to be sold as a dietary supplement. In the UK, piracetam is prescribed mainly for myoclonus, but is used off-label for other conditions. Evidence to support its use for many conditions is unclear.
基本信息
- 中文名称：
- 乙酰胺吡咯烷酮
- 中文别名：
- 吡拉西坦;
吡乙酰胺;
2-氧代-1-吡咯烷乙酰胺;
吡拉西坦;
2-氧代-1-吡咯烷基乙酰胺;
- 英文名称：
- 2-(2-oxopyrrolidin-1-yl)acetamide
- 英文别名：
- 2-Oxo-1-pyrrolidineacetamide;
Nootropil;
Normabrain;
Piracetam;
piracetam;
查看更多英文别名
- CAS号：
- 7491-74-9
- 分子式：
- C6H10N2O2
- 分子量：
- 142.15600
- 精确质量：
- 142.07400
- PSA：
- 63.40000
物化性质
- 密度：
- 1.239 g/cm3
- 熔点：
- 151-152ºC
- 沸点：
- 408.3ºC at 760 mmHg
- 闪点：
- 200.8ºC
- 折射率：
- 1.523
- 稳定性：
- Stable at normal temperatures and pressures.
- 储存条件：
- Keep tightly closed.
安全信息
- WGK Germany：2
- 危险类别码：R36/37/38
- 安全说明：S26; S37/39
- RTECS号：UX9660500
- 危险品标志：Xi
生产方法及用途
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生产方法
以2-吡咯烷酮为起始原料，在甲苯中与甲醇钠成盐，与氯代乙酸乙酯缩合后再氨化制得
用途
适用于急、慢性脑血管病、脑外伤、各种中毒性脑病等多种原因所致的记忆减退及轻、中度脑功能障碍。也可用于儿童智能发育迟缓。
