β-酮酯，丙二酸酯，α-氰基酯或α-磺酰基酯在亲核试剂存在下脱羧的反应

反应机理

反应实例

参考文献

1. Krapcho, A. P.; Glynn, G. A.; Grenon, B. J. Tetrahedron Lett. 1967, 215 217. A. Paul Krapcho is a professor at the University of Vermont.

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4. Martin, C. J.; Rawson, D. J.; Williams, J. M. J. Tetrahedron: Asymmetry 1998, 9, 3723-3730.

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8. Farran, D.; Bertrand, P. Synth. Commun. 2012, 42, 989-1001.

9. Adepu, R.; Rambabu, D.; Prasad, B.; Meda, C. L. T.; Kandale, A.; Rama Krishna, G.;Malla Reddy, C.; Chennuru, L. N. Org. Biomol. Chem. 2012, 10, 5554-5569.

10. Mason, J. D.; Murphree, S. S. Synlett 2013, 24, 1391–1394.

编译自：Name Reactions （A Collection of Detailed Reaction Mechanisms）, Jie Jack Li, Krapcho reaction，page 356.